By Adrianna Moore
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Additional info for Alginic acid : chemical structure, uses and health benefits
621-30. Smidsrod, O. and G. Skjak-Braek, Alginate as immobilization matrix for cells. Trends in Biotechnology, 1990. 8: p. 71-78. , H. Grasdalen, and B. Larsen, Monomer sequence and acetylation pattern in some bacterial alginates. Carbohydr. , 1986. 154: p. 239-50. d'Ayala, G. , M. Malinconico, and P. Laurienzo, Marine derived polysaccharides for biomedical applications: chemical modification approaches. Molecules, 2008. 13(9): p. 2069-106. 36 A. Martínez, E. Pérez, N. Montero et al.  Pawar, S.
For these reasons, it is necessary to develop new encapsulation approaches to protect the viability of probiotic cultures. Extrusion, emulsification and spray drying are the three major techniques for probiotic encapsulation [123, 125]. Kamalian et al. investigated the effect of Na-alginate-chitosan coated materials on the viability and release behaviour of encapsulated Bifidobacterium pseudocatenulatum G4 by emulsification technique . Alginate–chitosan capsules were more resistant than non-coated alginate capsules in acidic media.
In the 22 A. Martínez, E. Pérez, N. Montero et al. emulsification method, an alginate solution is mixed with the oil phase obtaining a w/o emulsion with small alginate droplets which are then externally or internally gelled. By controlling the conditions under which the water-in-oil dispersion is produced, the particle size can be controlled from a few microns to millimeters in diameter . Finally, the coacervation method uses oppositely charged polyelectrolytes to form bi-layer equilibrium phases under specific pH and ionic conditions, causing the dense coacervate phase to form microspheres .
Alginic acid : chemical structure, uses and health benefits by Adrianna Moore